We value your privacy

We use cookies to enhance your browsing experience, serve personalized ads or content, and analyze our traffic. By clicking "Accept All", you consent to our use of cookies.

Privacy Policy

Nutropica
CJC-1295 supplement image

CJC-1295

Description

CJC-1295 is a synthetic peptide, a long-acting analog of Growth Hormone-Releasing Hormone (GHRH), which has been studied since the early 2000s for its therapeutic potential. It works by stimulating the pituitary gland to release more Growth Hormone (GH), which in turn leads to increased levels of Insulin-Like Growth Factor I (IGF-I), and it's primarily known for its ability to produce sustained elevations of these hormones. Studies, such as a notable 2006 trial, have shown that CJC-1295 can increase mean plasma GH concentrations by 2- to 10-fold for six days or more and IGF-I concentrations by 1.5- to 3-fold for 9 to 11 days after a single administration in healthy adults.

Table of Contents

Back to All Nootropics

Categories & Effectiveness

Physical Performance

Muscle Growth

7/10

Strong evidence of effectiveness

Exercise Recovery

4/10

Moderate evidence of effectiveness

Strength & Power

4/10

Moderate evidence of effectiveness

Systemic Health

Cellular Repair

7/10

Strong evidence of effectiveness

Recommended Products

hochdosierte Omega 3 Kapseln 1000mg 30 Stück - mit EPA & DHA - Essentielle Omega 3 Fettsäuren aus Fischöl - Unterstützt Herz, Gehirn & Sehkraft - Ideal für Keto, Low-Carb & hCG-Stoffwechselkur

hochdosierte Omega 3 Kapseln 1000mg 30 Stück - mit EPA & DHA - Essentielle Omega 3 Fettsäuren aus Fischöl - Unterstützt Herz, Gehirn & Sehkraft - Ideal für Keto, Low-Carb & hCG-Stoffwechselkur

(14)
  • Rated 4.7 stars by 14 customers
  • Premium quality ingredients
€14.90

As an Amazon Associate we earn from qualifying purchases. Prices and availability are accurate as of the date/time indicated and are subject to change.

Dosage & Side Effects

Recommended Dosage

Commonly studied doses for adults are in the range of 30 to 60 micrograms per kilogram (mcg/kg) of body weight, administered subcutaneously. While these doses were found to be well-tolerated and effective in studies, optimal dosing can vary, and cumulative effects have been observed with multiple doses. The available research primarily focuses on healthy adults aged 21-61, so considerations for other populations may differ.

Potential Side Effects

While generally reported as safe and relatively well-tolerated in clinical studies, some individuals may experience mild, transient side effects common with GH-releasing peptides, such as injection site reactions (redness, itching, or soreness), flushing, or headaches. Serious adverse reactions were not reported in key studies at doses of 30 or 60 mcg/kg. Individuals with pre-existing medical conditions, particularly those sensitive to hormonal changes, should consult a healthcare professional before considering CJC-1295.

Bioavailability & Half-Life

CJC-1295 is administered via subcutaneous injection, allowing for direct absorption into the bloodstream. Following a single injection, it demonstrates a long duration of action, with an estimated elimination half-life of approximately 5.8 to 8.1 days. This extended half-life contributes to sustained increases in Growth Hormone (GH) levels for 6 days or more and Insulin-Like Growth Factor I (IGF-I) levels for 9 to 11 days or even longer with multiple doses, up to 28 days. The specific metabolic pathways are not detailed in the provided research summary.

Benefits by Use Case

Muscle Growth

May promote muscle growth by significantly increasing Growth Hormone and IGF-I levels, which are crucial for anabolism. Effects are typically observed with consistent administration and alongside appropriate physical training and nutrition.

Cellular Repair

Can support systemic cellular repair and regeneration processes due to elevated GH and IGF-I, which play roles in tissue maintenance and healing. Specific outcomes can vary, and this is a general physiological effect.

Enhanced Exercise Recovery

Potentially aids in faster recovery from exercise by promoting tissue repair and reducing inflammation through GH and IGF-I pathways. Individual recovery benefits can depend on exercise intensity and other factors.

Increased Strength

May contribute to strength gains over time, secondary to increased muscle mass and improved recovery. Direct acute effects on strength are less pronounced than long-term adaptive changes.

Where to Buy CJC-1295

Based on quality, price, and customer reviews, here are our top recommended CJC-1295 supplements:

OPC Traubenkernextrakt - 240 hochdosierte Kapseln für 8 Monate - Reines OPC aus europäischen Weintrauben - Vegan, in Deutschen Laboren getestet

OPC Traubenkernextrakt - 240 hochdosierte Kapseln für 8 Monate - Reines OPC aus europäischen Weintrauben - Vegan, in Deutschen Laboren getestet

(15,592)
  • Rated 4.6 stars by 15,592 customers
  • Premium quality ingredients
€27.99

As an Amazon Associate we earn from qualifying purchases. Prices and availability are accurate as of the date/time indicated and are subject to change.

Mechanism of Action

CJC-1295 is a synthetic peptide analog of Growth Hormone-Releasing Hormone (GHRH). It functions by binding to GHRH receptors in the anterior pituitary gland, mimicking the action of endogenous GHRH. This binding stimulates the synthesis and pulsatile release of Growth Hormone (GH). The increased GH in circulation then travels to the liver and other tissues, stimulating the production and release of Insulin-Like Growth Factor I (IGF-I). CJC-1295 is specifically designed for a long duration of action, allowing for sustained elevation of both GH and IGF-I levels, which mediate its downstream physiological effects such as promoting cell growth, reproduction, and regeneration.

Frequently Asked Questions

Summary & Expert Opinion

CJC-1295 is a long-acting GHRH analog that effectively and sustainably increases Growth Hormone and IGF-I levels in healthy adults, demonstrating good tolerability in research settings. Its primary strengths are its prolonged duration of action, reducing dosing frequency, and its dose-dependent efficacy in elevating key growth-related hormones. However, it requires subcutaneous administration, and its use is primarily investigational or for specific therapeutic applications under medical guidance. Healthy adults seeking to explore benefits associated with increased GH and IGF-I levels, such as muscle growth or enhanced recovery, might consider it, always prioritizing consultation with a healthcare professional. Individuals with hormone-sensitive conditions, or those subject to anti-doping regulations, should avoid its use or proceed with extreme caution and medical supervision.

Complementary Products

These products pair well with CJC-1295 for enhanced benefits:

Large Weekly Pill Organizer, Pill Box 7 Day, KAPENS Daily Vitamin Case Large Capacity Compartments, Pill Containers for Fish Oil Medicine Supplements, Black

Large Weekly Pill Organizer, Pill Box 7 Day, KAPENS Daily Vitamin Case Large Capacity Compartments, Pill Containers for Fish Oil Medicine Supplements, Black

(4,311)
  • Rated 4.7 stars by 4,311 customers
  • Premium quality ingredients
$7.99

As an Amazon Associate we earn from qualifying purchases. Prices and availability are accurate as of the date/time indicated and are subject to change.

Research Studies

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. (2006)

GH increase IGF-I increase dose-dependent +2 more
Source

Similar Nootropics

Berberine supplement image

Berberine

 garlic supplement image

garlic

 Holy Basil supplement image

Holy Basil

 NAD supplement image

NAD